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Low-dose estrogen shown safe and effective for metastatic breast cancer

August 19, 2020

By Gwen Ericson, Washington University School of Medicine

When estrogen-lowering drugs no longer control metastatic breast cancer, the opposite strategy might work. Raising estrogen levels benefited 30 percent of women whose metastatic breast cancer no longer responded to standard anti-estrogen treatment, according to research conducted at Washington University School of Medicine in St. Louis and collaborating institutions.

The results are reported in the Aug. 19, 2009, issue of the Journal of the American Medical Association. Not only did estrogen treatment often stop disease progression, in some patients metastatic tumors became resensitized and again responded to anti-estrogen treatments.

FDA Expands Access to Investigational Drugs

August 13, 2020


Seriously ill patients who lack good treatments sometimes want to try a promising drug that is still under development. These patients often hope this drug will provide them with a lifeline where none had existed before.

Lack of Study Volunteers Hobbles Cancer Fight

August 11, 2020

By Gina Kolata, New York Times

Not long ago, at a meeting of an advisory group established by Congress to monitor the war on cancer, participants were asked how to speed progress.

Considering Combination Versus Sequential Chemotherapy In Metastatic Breast Cancer

August 6, 2020

By Science Daily

Both combination and sequential single-agent chemotherapy are reasonable options to treat metastatic breast cancer, but the choice between the two should ultimately be based on patient- and disease-related factors, according to a new commentary published online August 5 in the Journal of the National Cancer Institute.